Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525664 | 0.85 | RXFP1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL27512818 | 0.75 | TDO2 (0.32) | NTRK1PIK3CAPIK3CG | |
| Hydrochloric Acid SCHEMBL7740435 | 0.75 | TDO2 (0.32) | NTRK1PIK3CAPIK3CG | |
| SCHEMBL7734196 | 0.70 | HDAC3 (0.32) | — | |
| SCHEMBL7740420 | 0.68 | SYK (0.37) | — | |
| SCHEMBL7734182 | 0.65 | GRM2 (0.33) | NTRK1PIK3CAPIK3CG | |
| SCHEMBL7740424 | 0.65 | MEN1 (0.36) | — | |
| SCHEMBL8116723 | 0.65 | TDO2 (0.33) | NTRK1PIK3CAPIK3CG | |
| SCHEMBL7734178 | 0.64 | NTRK1 (0.35) | NTRK1PIK3CAPIK3CG | |
| SCHEMBL7740476 | 0.64 | NOS1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1217928-C | Heterocyclic compound having NOS inhibitory action | CHUGAI SEIYAKA K K (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1280565-A | Heterocyclic compounds having NOS inhibitory activities | CHUGAI SEIYAKA K K (JP) | 2001-01-17 | — | — | CN | disclosed |