Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 3/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587710 | 0.93 | HSD17B1 (0.41) | HSD17B1HSD17B2RAB9AAKR1C4AKR1C3 | |
| SCHEMBL6816973 | 0.81 | KMO (0.39) | AKR1C3ALDH1A1TSHRCYP2C9PARP1 | |
| SCHEMBL6820924 | 0.77 | AKR1B1 (0.41) | TSHR | |
| SCHEMBL11804404 | 0.77 | ALDH1A1 (0.52) | HSD17B1HSD17B2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL27499553 | 0.77 | ACMSD (0.43) | AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL6920197 | 0.72 | ALDH1A1 (0.41) | RAB9AALDH1A1PTPN1NPC1 | |
| SCHEMBL27516293 | 0.71 | KDM4E (0.38) | RAB9AALDH1A1TSHRCYP3A4NPC1 | |
| SCHEMBL27499554 | 0.71 | ALDH1A1 (0.40) | RAB9AALDH1A1TSHRNPC1IKBKB | |
| SCHEMBL27519456 | 0.70 | MMP2 (0.44) | AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL5594733 | 0.70 | MMP2 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |