Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631088 | 0.89 | TPSAB1 (0.40) | PTPN1KDM4EPTPRCALDH1A1MAPT | |
| SCHEMBL27611938 | 0.88 | MEN1 (0.38) | PTPN1KDM4ELMNAPTPRCALDH1A1 | |
| SCHEMBL27395268 | 0.88 | ALDH1A1 (0.49) | PTPN1PTPRCALDH1A1MEN1KMT2A | |
| SCHEMBL27621123 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6770770 | 0.78 | RAB9A (0.39) | PTPN1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9437629 | 0.77 | PKM (0.34) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL8954959 | 0.76 | FFAR1 (0.41) | LMNA | |
| SCHEMBL27611924 | 0.76 | KDM4E (0.39) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL9437511 | 0.75 | LMNA (0.50) | KDM4ELMNAALDH1A1MAPTHTT | |
| SCHEMBL14935151 | 0.73 | MAOA (0.47) | KDM4EALDH1A1MAPTNPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688298-A | Composition, Synthesis and Therapeutic Use of Polyamines | MURPHY MICHAEL A (US) | 2005-10-26 | — | — | CN | claimed |