SCHEMBL2770000

SCHEMBL2770000

O=C1CCc2ccc3[nH]cnc3c2NN1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
PARP1 P09874 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
PNP P00491 1/20 0.32
BRD4 O60885 1/20 0.32
ALDH1A1 P00352 2/20 0.31
PRNP P04156 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
DPP4 P27487 1/20 0.31
PKM P14618 1/20 0.31
PDE2A O00408 1/20 0.30
PDE1A P54750 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE1C Q14123 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694803 0.81 LMNA (0.33) LMNAPARP1MEN1KMT2APOLB
SCHEMBL4667412 0.71 LMNA (0.35) LMNAPARP1MEN1KMT2APOLB
SCHEMBL23840126 0.65 NOS3 (0.39) LMNAPARP1MEN1KMT2APOLB
SCHEMBL7846846 0.65 BRD4 (0.40) LMNAPARP1MEN1KMT2APOLB
SCHEMBL5726226 0.62 BRD4 (0.41) LMNAPARP1MEN1KMT2APOLB
SCHEMBL28937348 0.61 CD44 (0.41) LMNAMEN1KMT2APOLB
SCHEMBL5873892 0.61 GSK3B (0.37) LMNAPARP1CSNK2A1DYRK1A
SCHEMBL31632446 0.60 LMNA (0.34) LMNAPARP1MEN1KMT2APOLB
SCHEMBL4114394 0.60 LMNA (0.34) LMNAPARP1MEN1KMT2APOLB
SCHEMBL15834705 0.59 LMNA (0.44) LMNAPARP1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082685-A1 METHODS FOR ATTENUATING VIRAL INFECTION AND FOR TREATING LUNG INJURY Spiritus Therapeutics, Inc. (US) 2025-03-13 US claimed
WO-2023081299-A9 A PURIFIED ENRICHED POPULATION EXOSOMES DERIVED FROM INDIVIDUALS WITH A CHRONIC PROGRESSIVE LUNG DISEASE FOR NONINVASIVE DETECTION, STAGING, AND MEDICAL MONITORING OF DISEASE PROGRESSION Spiritus Therapeutics, Inc. (US) 2024-03-21 WO claimed
EP-4267958-A2 METHOD FOR SMALL-RNA BIOMARKER IDENTIFICATION AND FUNCTIONAL EVALUATION OF CIRCULATING EXTRACELLULAR VESICLES COMPRISING EXOSOMES Hackensack Meridian Health Center for Discovery and Innovation (US) 2023-11-01 EP claimed
WO-2023178169-A2 COMPOSITIONS AND METHODS FOR TREATING THE PATHOPHYSIOLOGY OF SEVERE VIRAL INFECTION ANEMOI BIOTECH HOLDINGS, INC. (US) 2023-09-21 WO claimed
WO-2023081299-A1 A PURIFIED ENRICHED POPULATION EXOSOMES DERIVED FROM INDIVIDUALS WITH A CHRONIC PROGRESSIVE LUNG DISEASE FOR NONINVASIVE DETECTION, STAGING, AND MEDICAL MONITORING OF DISEASE PROGRESSION Spiritus Therapeutics, Inc. (US) 2023-05-11 WO claimed
US-20230147720-A1 Purified Enriched Population Exosomes Derived From Individuals With A Chronic Progressive Lung Disease For Noninvasive Detection, Staging, And Medical Monitoring Of Disease Progression Spiritus Therapeutics, Inc. (US) 2023-05-11 US claimed
US-20220401477-A1 METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERACTIVATED CYTOKINE KILLER CELLS VERDURE BIOTECH, INC. (US) 2022-12-22 US claimed
WO-2022245813-A2 A METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERCTIVATED CYTOKINE KILLER CELLS VERDURE BIOTECH, INC. (US) 2022-11-24 WO claimed
WO-2022140662-A2 METHOD FOR SMALL-RNA BIOMARKER IDENTIFICATION AND FUNCTIONAL EVALUATION OF CIRCULATING EXTRACELLULAR VESICLES COMPRISING EXOSOMES Hackensack Meridian Health Center For Discovery and Innovation (US) 2022-06-30 WO claimed
US-20200384034-A1 METHODS FOR ATTENUATING VIRAL INFECTION AND FOR TREATING LUNG INJURY Spiritus Therapeutics, Inc. (US) 2020-12-10 US claimed
WO-2020247675-A1 METHODS FOR ATTENUATING VIRAL INFECTION AND FOR TREATING LUNG INJURY Spiritus Therapeutics, Inc. (US) 2020-12-10 WO claimed
US-12607589-B2 Methods, assays and systems for detection of a target analyte SORRENTO THERAPEUTICS, INC. (US) 2026-04-21 US disclosed
US-20250082685-A1 METHODS FOR ATTENUATING VIRAL INFECTION AND FOR TREATING LUNG INJURY Spiritus Therapeutics, Inc. (US) 2025-03-13 US disclosed
US-12097222-B2 Methods for attenuating viral infection and for treating lung injury Spiritus Therapeutics, Inc. (US) 2024-09-24 US disclosed
US-20240302317-A1 Methods, Assays and Systems for Detection of a Target Analyte SORRENTO THERAPEUTICS, INC. 2024-09-12 US disclosed
US-6040346-A Use of L-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral drugs SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2000-03-21 US disclosed
WO-1999036384-A1 ALKENYLDIARYLMETHANE NON-NUCLEOSIDE HIV-1 REVERSE TRANSCRIPTASE INHIBITORS PURDUE RESEARCH FOUNDATION (US) 1999-07-22 WO disclosed
EP-0839033-A2 USE OF L-CARNITINE AND DERIVATIVES FOR REDUCING CERAMIDE LEVELS AND POTENTIATING ANTIRETROVIRAL Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1998-05-06 EP disclosed
WO-1997005864-A2 USE OF L-CARNITINE AND DERIVATIVES FOR REDUCING CERAMIDE LEVELS AND POTENTIATING ANTIRETROVIRAL DRUGS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1997-02-20 WO disclosed
EP-0574781-A2 2-Amino-5-heterocyclic-substituted-1,4-benzodiazepines and their use in the treatment of aids F. HOFFMANN-LA ROCHE AG (CH) 1993-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401477-A1 METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERACTIVATED CYTOKINE KILLER CELLS IFNG, PBK, IL4 LMNA 1485/4885PARP1 3057/4885MEN1 3532/4885
US-12607589-B2 Methods, assays and systems for detection of a target analyte PRSS3, PRSS2, ZP1 LMNA 2280/4885PARP1 3487/4885MEN1 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.