Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glyceryl Monostearate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.93 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.93 |
| ▸ | MEN1 | O00255 | 1/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.93 |
| ▸ | DGKA | P23743 | 1/20 | 0.78 |
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PRKCA | P17252 | 3/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.61 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.61 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyceryl Monostearate SCHEMBL27785909 | 0.97 | LMNA (0.93) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2119138 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2326840 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glyceryl Monostearate SCHEMBL2489632 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21685815 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glyceryl Monostearate SCHEMBL1653474 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glycerol Monopalmitate SCHEMBL977143 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glyceryl Monostearate SCHEMBL4488 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL10937708 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Monoctanoin Component B SCHEMBL22366087 | 0.97 | LMNA (1.00) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160113-A | Soaps from organic residues and method of producing the same | TAZPIT KEFAR NACHUM SHEMEN ZAI (IL) | 2008-04-09 | — | — | CN | disclosed |