Sugi Predict

Sugi Predict / Compounds / SCHEMBL5951586

SCHEMBL5951586

SCHEMBL5951586

Fc1cccc2[nH]ncc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AXL P30530 2/20 0.63
▸ NOS1 P29475 4/20 0.59
▸ IDO1 P14902 3/20 0.55
▸ METAP2 P50579 2/20 0.53
▸ NPC1 O15118 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ JAK2 O60674 1/20 0.46
▸ JAK1 P23458 1/20 0.46
▸ HSP90AA1 P07900 1/20 0.45
▸ CDK2 P24941 1/20 0.45
▸ PIM3 Q86V86 1/20 0.44
▸ MET P08581 1/20 0.43
▸ RAF1 P04049 1/20 0.43
▸ BRAF P15056 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30469214 1.00 AXL (0.63) AXLNOS1IDO1METAP2NPC1
SCHEMBL28198038 0.83 METAP2 (0.64) AXLNOS1IDO1METAP2HSP90AA1
SCHEMBL12683720 0.78 AXL (1.00) AXLNOS1IDO1METAP2JAK2
SCHEMBL20593926 0.77 AXL (0.45) AXLNOS1IDO1METAP2NPC1
SCHEMBL30018079 0.77 AXL (0.45) AXLNOS1IDO1METAP2NPC1
SCHEMBL12601112 0.76 NOS1 (0.61) AXLNOS1IDO1METAP2NPC1
SCHEMBL18193497 0.74 NOS1 (0.59) AXLNOS1IDO1METAP2NPC1
SCHEMBL476854 0.74 NOS1 (1.00) AXLNOS1IDO1METAP2CYP1A2
SCHEMBL155255 0.74 NOS1 (1.00) AXLNOS1IDO1METAP2NPC1
SCHEMBL277054 0.74 NOS1 (0.59) AXLNOS1IDO1METAP2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119020039-A Long-life chip cleaning liquid for stably etching TiN, preparation method and application thereof 浙江奥首材料科技有限公司 2024-11-26 — — CN claimed
CN-111995577-A Synthetic method of 4-fluoro indazole 3-carbonitrile or derivatives thereof 上海代为化学科技有限公司 2020-11-27 — — CN claimed
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
EP-4688751-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS Enanta Pharmaceuticals, Inc. (US) 2026-02-11 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
EP-4624465-A1 COMPOUND SERVING AS DDR1 KINASE INHIBITOR, AND MEDICINE Nippon Shinyaku Co., Ltd. (JP) 2025-10-01 — — EP disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
US-20250214942-A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-07-03 — — US disclosed
US-12286406-B2 Inhibitors of receptor interacting protein kinase I for the treatment of disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-29 — — US disclosed
US-12275720-B2 Small molecule inhibitors of galectin-3 BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-15 — — US disclosed
US-8288425-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2012-10-16 — — US disclosed
US-8288425-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2012-10-16 — — US disclosed
WO-2012106995-A1 RORGAMMAT INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-08-16 — — WO disclosed
WO-2012106995-A1 RORGAMMAT INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-08-16 — — WO disclosed
WO-2009106577-A1 IMIDAZO [1,2-B] PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF C-MET TYROSINE KINASE MEDIATED DISEASE NOVARTIS AG (CH) 2009-09-03 — — WO disclosed
US-20060014756-A1 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2006-01-19 — — US disclosed
US-6897208-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2005-05-24 — — US disclosed
US-20040048868-A1 Benzimidazoles AVENTISUB LLC 2004-03-11 — — US disclosed
US-4778511-A FOR PLANTS AND MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1988-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014756-A1 Benzimidazoles CDK9, BMX, SBK3 AXL 689/4885NOS1 2282/4885IDO1 1783/4885
US-12275720-B2 Small molecule inhibitors of galectin-3 LGALS3, LGALS3BP, LGALS1 AXL 1230/4885NOS1 1767/4885IDO1 1007/4885
US-20250214942-A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE RIPK1, RIPK2, RIPK4 AXL 2450/4885NOS1 3272/4885IDO1 3786/4885
US-20040048868-A1 Benzimidazoles CDK9, BMX, CDKN1A AXL 723/4885NOS1 1270/4885IDO1 1021/4885
US-12286406-B2 Inhibitors of receptor interacting protein kinase I for the treatment of disease RIPK1, RIPK2, RIPK4 AXL 2450/4885NOS1 3272/4885IDO1 3786/4885
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB AXL 4487/4885NOS1 3827/4885IDO1 3088/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB AXL 4487/4885NOS1 3827/4885IDO1 3088/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB AXL 4487/4885NOS1 3827/4885IDO1 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.