Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109160 | 0.88 | PARP10 (0.53) | LMNAKMT2AMEN1HSD11B1 | |
| SCHEMBL28753553 | 0.87 | MGLL (0.52) | LMNAKMT2AMEN1POLBHSD11B1 | |
| SCHEMBL27713229 | 0.85 | GAA (0.55) | LMNAKMT2AMEN1POLBHSD11B1 | |
| SCHEMBL22031741 | 0.84 | KMT2A (0.51) | LMNAKMT2AMEN1POLBL3MBTL3 | |
| SCHEMBL22031711 | 0.83 | LMNA (0.43) | LMNAKMT2APOLBL3MBTL3L3MBTL1 | |
| SCHEMBL28238844 | 0.81 | KMT2A (0.46) | LMNAKMT2AMEN1POLBL3MBTL3 | |
| SCHEMBL27713245 | 0.81 | RAB9A (0.53) | LMNAKMT2APOLBL3MBTL3L3MBTL1 | |
| SCHEMBL7809522 | 0.80 | ACHE (0.64) | ACHEEPHX1KMT2AMEN1BACE1 | |
| SCHEMBL4678438 | 0.80 | ACHE (0.63) | ACHEEPHX1KMT2AMEN1BACE1 | |
| SCHEMBL2757942 | 0.80 | LMNA (0.85) | LMNAACHEEPHX1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |