Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127245 | 0.84 | L3MBTL3 (0.43) | KMT2APOLBL3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL28753553 | 0.82 | MGLL (0.52) | KMT2APOLBLMNAMEN1 | |
| SCHEMBL27733598 | 0.81 | LMNA (0.57) | KMT2APOLBLMNAL3MBTL3L3MBTL1 | |
| SCHEMBL22031741 | 0.81 | KMT2A (0.51) | KMT2APOLBLMNAL3MBTL3MEN1 | |
| SCHEMBL27713229 | 0.80 | GAA (0.55) | KMT2APOLBLMNAMEN1HPGD | |
| SCHEMBL19127198 | 0.78 | NAMPT (0.57) | KMT2AMEN1TGFBR1ABL1RIN1 | |
| SCHEMBL27713245 | 0.76 | RAB9A (0.53) | KMT2APOLBLMNAL3MBTL3L3MBTL1 | |
| SCHEMBL15317795 | 0.74 | L3MBTL3 (0.71) | KMT2AL3MBTL3MBTD1L3MBTL1TP53BP1 | |
| SCHEMBL19126527 | 0.73 | KMT2A (0.60) | KMT2APOLBLMNAMEN1TGFBR1 | |
| SCHEMBL22031711 | 0.73 | LMNA (0.43) | KMT2APOLBLMNAL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473485-A | QUINOLIN-2-ONE DERIVATIVES | 默克专利股份公司 | 2018-08-31 | — | — | CN | disclosed |