Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753553 | 0.85 | MGLL (0.52) | HSD11B1KMT2AMEN1MGLLPOLB | |
| SCHEMBL27733598 | 0.85 | LMNA (0.57) | HSD11B1KMT2AMEN1POLBLMNA | |
| SCHEMBL22031741 | 0.82 | KMT2A (0.51) | GAAHSD11B1KMT2AMEN1TSHR | |
| SCHEMBL28238844 | 0.80 | KMT2A (0.46) | KMT2AMEN1HPGDPOLBLMNA | |
| SCHEMBL27713245 | 0.79 | RAB9A (0.53) | GAAKMT2AHPGDPOLBEPHX2 | |
| SCHEMBL30964009 | 0.79 | GAA (0.73) | GAATDP1HSD11B1TEAD1KMT2A | |
| SCHEMBL22499928 | 0.79 | NOTUM (0.53) | — | |
| SCHEMBL28597269 | 0.79 | NOTUM (0.53) | — | |
| SCHEMBL27713265 | 0.77 | SFRP1 (0.46) | KMT2AHPGDPOLBLMNA | |
| SCHEMBL23775473 | 0.76 | GAA (0.74) | GAATDP1HSD11B1TEAD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |