Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753553 | 0.86 | MGLL (0.52) | EPHX2POLBKMT2ALMNA | |
| SCHEMBL27713265 | 0.86 | SFRP1 (0.46) | HPGDPOLBKMT2ASFRP1LMNA | |
| SCHEMBL27718555 | 0.81 | CHRM4 (0.45) | GAACHRNB2CHRNA4 | |
| SCHEMBL27733598 | 0.81 | LMNA (0.57) | POLBKMT2ALMNAL3MBTL3L3MBTL1 | |
| SCHEMBL27713229 | 0.79 | GAA (0.55) | EPHX2GAAHPGDPOLBKMT2A | |
| SCHEMBL22031741 | 0.78 | KMT2A (0.51) | RAB9AEPHX2GAAGRM5POLB | |
| SCHEMBL4736618 | 0.78 | RAB9A (0.58) | RAB9AEPHX2GRM5HPGDSFRP1 | |
| SCHEMBL4616966 | 0.77 | EPHX2 (0.59) | RAB9AEPHX2GRM5HPGDKMT2A | |
| SCHEMBL13202942 | 0.77 | RAB9A (0.57) | RAB9AEPHX2GRM5HPGDSFRP1 | |
| SCHEMBL14393777 | 0.76 | RAB9A (0.63) | RAB9AEPHX2GRM5HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |