Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713329 | 0.92 | AR (0.39) | HSD11B1PTGDR2PPARGPPARAMEN1 | |
| SCHEMBL27733647 | 0.86 | PTGDR2 (0.38) | HSD11B1PTGDR2MCL1PPARGPPARA | |
| SCHEMBL27713340 | 0.83 | ATM (0.41) | ALDH1A1LMNAATM | |
| SCHEMBL27733871 | 0.83 | KDM4E (0.44) | MAPTKMT2AESR1 | |
| SCHEMBL27733782 | 0.82 | KDM4E (0.43) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL28770872 | 0.81 | PDGFRB (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27713332 | 0.81 | MEN1 (0.42) | MEN1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL27713445 | 0.81 | BCAT1 (0.45) | PPARGALDH1A1MAPTNPSR1 | |
| SCHEMBL27713316 | 0.80 | HRH3 (0.37) | MMP2MMP13MEN1ALDH1A1MAPT | |
| SCHEMBL27733691 | 0.79 | ELANE (0.41) | MEN1NPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |