Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PLD2 | O14939 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733691 | 0.91 | ELANE (0.41) | HRH3PDGFRBPDGFRACTNNB1WNT3A | |
| SCHEMBL27733782 | 0.87 | KDM4E (0.43) | PDGFRBPDGFRAALDH1A1HPGDMEN1 | |
| SCHEMBL28770872 | 0.87 | PDGFRB (0.43) | PDGFRBPDGFRABCAT1ALDH1A1MAPT | |
| SCHEMBL27713340 | 0.86 | ATM (0.41) | PDGFRBPDGFRAALDH1A1HPGDTSHR | |
| SCHEMBL27713445 | 0.86 | BCAT1 (0.45) | HRH3PDGFRBPDGFRAHRH4BCAT1 | |
| SCHEMBL27713332 | 0.86 | MEN1 (0.42) | HRH3HRH4BCAT1ALDH1A1MAPT | |
| SCHEMBL27713329 | 0.83 | AR (0.39) | PDGFRBPDGFRAHRH4HDAC2CTNNB1 | |
| SCHEMBL27733871 | 0.82 | KDM4E (0.44) | PDGFRBPDGFRAHDAC2BCAT1MAPT | |
| SCHEMBL27733651 | 0.80 | MMP2 (0.38) | MMP2MMP13ALDH1A1MAPTMEN1 | |
| SCHEMBL27713298 | 0.79 | GPR27 (0.34) | PDGFRBPDGFRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |