Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733782 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL28770872 | 0.88 | PDGFRB (0.43) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL27713445 | 0.87 | BCAT1 (0.45) | ALDH1A1CYP2C19FLT3PYGLPDGFRB | |
| SCHEMBL27713332 | 0.87 | MEN1 (0.42) | KDM4EALDH1A1LMNAPYGL | |
| SCHEMBL27713329 | 0.86 | AR (0.39) | ATMALDH1A1LMNAPDGFRBPDGFRA | |
| SCHEMBL27713316 | 0.86 | HRH3 (0.37) | ALDH1A1HPGDTSHRPDGFRBPDGFRA | |
| SCHEMBL27733691 | 0.85 | ELANE (0.41) | ALDH1A1LMNAHPGDTSHRPDGFRB | |
| SCHEMBL27733871 | 0.85 | KDM4E (0.44) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL27713298 | 0.84 | GPR27 (0.34) | ATMPYGLPDGFRBPDGFRA | |
| SCHEMBL27733651 | 0.83 | MMP2 (0.38) | ATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |