Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733782 | 0.89 | KDM4E (0.43) | PDGFRBPDGFRAKDM4ETP53ALDH1A1 | |
| SCHEMBL27713340 | 0.88 | ATM (0.41) | PDGFRBPDGFRAKDM4ELMNAALDH1A1 | |
| SCHEMBL27713332 | 0.88 | MEN1 (0.42) | KDM4ELMNABCAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27713445 | 0.88 | BCAT1 (0.45) | PDGFRBPDGFRABCAT1ALDH1A1MAPT | |
| SCHEMBL27713316 | 0.87 | HRH3 (0.37) | PDGFRBPDGFRABCAT1ALDH1A1HPGD | |
| SCHEMBL27733691 | 0.86 | ELANE (0.41) | PDGFRBPDGFRALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27733647 | 0.85 | PTGDR2 (0.38) | KDM4ETP53L3MBTL1HSD17B10HPGD | |
| SCHEMBL27713329 | 0.85 | AR (0.39) | PDGFRBPDGFRALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27733871 | 0.83 | KDM4E (0.44) | PDGFRBPDGFRAKDM4EBCAT1MAPT | |
| SCHEMBL27713298 | 0.82 | GPR27 (0.34) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |