Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713329 | 0.92 | AR (0.39) | PTGDR2HSD11B1L3MBTL1ESR1NPSR1 | |
| SCHEMBL27733651 | 0.86 | MMP2 (0.38) | PTGDR2HSD11B1ESR1NPSR1MAPT | |
| SCHEMBL28770872 | 0.85 | PDGFRB (0.43) | L3MBTL1TP53MAPTHPGDHSD17B10 | |
| SCHEMBL27713340 | 0.80 | ATM (0.41) | HPGDHSD17B10KDM4E | |
| SCHEMBL27733871 | 0.80 | KDM4E (0.44) | ESR1MAPTKMT2AKDM4E | |
| SCHEMBL27713298 | 0.80 | GPR27 (0.34) | NPSR1KMT2APPARGPPARA | |
| SCHEMBL27733782 | 0.79 | KDM4E (0.43) | TP53HPGDRAB9AKMT2AHSD17B10 | |
| SCHEMBL27713332 | 0.78 | MEN1 (0.42) | MAPTRAB9AKMT2AKDM4E | |
| SCHEMBL27713445 | 0.78 | BCAT1 (0.45) | NPSR1MAPTPPARG | |
| SCHEMBL27713316 | 0.77 | HRH3 (0.37) | MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |