Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770872 | 0.89 | PDGFRB (0.43) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL27713340 | 0.88 | ATM (0.41) | KDM4EALDH1A1HSD17B10HPGDPDGFRB | |
| SCHEMBL27713445 | 0.88 | BCAT1 (0.45) | ALDH1A1PDGFRBPDGFRAGAAFLT3 | |
| SCHEMBL27713332 | 0.88 | MEN1 (0.42) | KDM4EALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27713316 | 0.87 | HRH3 (0.37) | ALDH1A1HPGDPDGFRBPDGFRAKMT2A | |
| SCHEMBL27733691 | 0.86 | ELANE (0.41) | ALDH1A1RAB9AHPGDSMN1; SMN2PDGFRB | |
| SCHEMBL27713329 | 0.85 | AR (0.39) | ALDH1A1RAB9ASMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL27733871 | 0.83 | KDM4E (0.44) | KDM4EPDGFRBPDGFRAKMT2AGAA | |
| SCHEMBL27733651 | 0.82 | MMP2 (0.38) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27713298 | 0.81 | GPR27 (0.34) | PDGFRBPDGFRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |