Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733651 | 0.92 | MMP2 (0.38) | PTGDR2HSD11B1PPARGPPARAESR1 | |
| SCHEMBL27733647 | 0.92 | PTGDR2 (0.38) | PTGDR2HSD11B1PPARGPPARAL3MBTL1 | |
| SCHEMBL27713340 | 0.86 | ATM (0.41) | ARPDGFRBPDGFRAALDH1A1LMNA | |
| SCHEMBL27733871 | 0.86 | KDM4E (0.44) | PDGFRBPDGFRAESR1MAPTKMT2A | |
| SCHEMBL27733782 | 0.85 | KDM4E (0.43) | PDGFRBPDGFRAMEN1NPC1ALDH1A1 | |
| SCHEMBL28770872 | 0.85 | PDGFRB (0.43) | PDGFRBPDGFRAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL27713445 | 0.84 | BCAT1 (0.45) | HRH4PPARGPDGFRBPDGFRANPSR1 | |
| SCHEMBL27713332 | 0.84 | MEN1 (0.42) | HRH4EGFRMEN1NPC1ALDH1A1 | |
| SCHEMBL27713316 | 0.83 | HRH3 (0.37) | HRH4PDGFRBPDGFRACTNNB1MEN1 | |
| SCHEMBL27733691 | 0.82 | ELANE (0.41) | PDGFRBPDGFRAL3MBTL1CTNNB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |