Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713329 | 0.86 | AR (0.39) | KMT2APDGFRBPDGFRAMAPTESR1 | |
| SCHEMBL27713340 | 0.85 | ATM (0.41) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL27733782 | 0.83 | KDM4E (0.43) | KDM4EGAAKMT2APDGFRBPDGFRA | |
| SCHEMBL28770872 | 0.83 | PDGFRB (0.43) | KDM4EPDGFRBPDGFRAMAPTIDO1 | |
| SCHEMBL27733651 | 0.83 | MMP2 (0.38) | KMT2AMAPTESR1 | |
| SCHEMBL27713445 | 0.83 | BCAT1 (0.45) | GAAPDGFRBPDGFRAMAPTIDO1 | |
| SCHEMBL27713332 | 0.83 | MEN1 (0.42) | KDM4EKMT2AMAPTBCAT1 | |
| SCHEMBL27713316 | 0.82 | HRH3 (0.37) | KMT2APDGFRBPDGFRAMAPTBCAT1 | |
| SCHEMBL27733691 | 0.81 | ELANE (0.41) | KMT2APDGFRBPDGFRAMAPTCYP2C9 | |
| SCHEMBL27733647 | 0.80 | PTGDR2 (0.38) | KDM4EKMT2AMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |