Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17803140 | 0.85 | MEN1 (0.49) | LMNAAGXTFAAHMAPTMEN1 | |
| SCHEMBL29077216 | 0.84 | LMNA (0.51) | KMOLMNAAGXTFAAHAKR1C3 | |
| SCHEMBL3016819 | 0.83 | ALDH1A1 (0.47) | LMNAAKR1C3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL27818699 | 0.81 | ADRA2C (0.56) | AGXTFAAHPLOD2PLOD3PLOD1 | |
| SCHEMBL27329825 | 0.78 | LMNA (0.71) | KMOLMNAAGXTAKR1C3PIK3CD | |
| SCHEMBL20627137 | 0.78 | LMNA (0.55) | KMOLMNAAGXTFAAHAKR1C3 | |
| SCHEMBL4834394 | 0.78 | ADRB1 (0.65) | KMOLMNAAGXTFAAHPRKDC | |
| SCHEMBL28195870 | 0.77 | PRKDC (0.56) | KMOLMNAAGXTFAAHPIK3CA | |
| SCHEMBL875323 | 0.77 | KMO (0.55) | KMOLMNAAGXTAKR1C3PIK3CD | |
| SCHEMBL2597677 | 0.77 | LMNA (0.53) | KMOLMNAAGXTFAAHAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191888-A | Aziridine pleocidin derivative and preparation method | 阿格里麦蒂斯有限责任公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-109311888-A | Novel piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2019-02-05 | — | — | CN | disclosed |
| CN-105164113-A | Pyrroloamide inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |
| CN-101389324-A | Azaindole inhibitors of aurora kinases | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | CN | disclosed |