Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27818699 | 0.85 | ADRA2C (0.56) | MEN1KMT2AAGXTADRB1MAPT | |
| SCHEMBL27756289 | 0.85 | KMO (0.53) | MEN1KMT2AALDH1A1KDM4EAGXT | |
| SCHEMBL7684964 | 0.79 | HDAC6 (0.46) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5209026 | 0.78 | KCNH2 (0.47) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL30753410 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29718856 | 0.76 | CHRNB2 (0.51) | — | |
| SCHEMBL28782583 | 0.76 | CHRNB2 (0.51) | — | |
| SCHEMBL6677730 | 0.76 | ENPP2 (0.41) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL3051915 | 0.76 | ADRB1 (0.71) | MEN1KMT2AALDH1A1KDM4EADRB1 | |
| SCHEMBL30255158 | 0.76 | ADRB1 (0.71) | MEN1KMT2AALDH1A1KDM4EADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | claimed |
| US-10292970-B2 | Heteroaryl-substituted imidazo[1,2-A]pyridines and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20170304278-A1 | HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-10-26 | — | — | US | disclosed |
| EP-3227287-A1 | HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087343-A1 | HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
| CN-101888877-A | Pyridine derivatives for the treatment of amyloid-related diseases | SENEXIS LTD | 2010-11-17 | — | — | CN | disclosed |
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | disclosed |
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304278-A1 | HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | TNNI3, CYP11B2, PPIP5K2 | MEN1 1648/4885KMT2A 2454/4885ALDH1A1 676/4885 |
| US-10292970-B2 | Heteroaryl-substituted imidazo[1,2-A]pyridines and their use | TNNI3, CYP11B2, PPIP5K2 | MEN1 1648/4885KMT2A 2454/4885ALDH1A1 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.