Water

Water

SCHEMBL27775282

[8OH2]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28258609 1.00
SCHEMBL27468099 1.00
Methane SCHEMBL23088734 0.00
Methane SCHEMBL23795058 0.00
SCHEMBL23528133 0.00
SCHEMBL23461972 0.00
SCHEMBL25435013 0.00
Phosphine SCHEMBL25436453 0.00
Water SCHEMBL25437472 0.00
SCHEMBL23462191 0.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109569508-A Micro-pore carbon material separates the nitrogen in association and nonassociated gas stream 墨西哥石油研究院 2019-04-05 CN claimed
CN-108206229-A The production method of ITO pattern in a kind of GaN base LED 山东浪潮华光光电子股份有限公司 2018-06-26 CN claimed
CN-102816805-B Novel method for improving saccharic acid conversion rate of L-glutamic acid JILIN COFCO BIOCHEMICAL TECHNOLOGY CO LTD 2014-04-02 CN claimed
CN-102816805-A Novel method for improving saccharic acid conversion rate of L-glutamic acid JILIN COFCO BIOCHEMICAL TECHNOLOGY CO LTD 2012-12-12 CN claimed
CN-118109688-A Zinc-oxygen pressure leaching high-sulfur slag triple pyrogenic process recycling treatment method 呼伦贝尔驰宏矿业有限公司 2024-05-31 CN disclosed
CN-108206229-A The production method of ITO pattern in a kind of GaN base LED 山东浪潮华光光电子股份有限公司 2018-06-26 CN disclosed
CN-107437502-A The method that oxidation processes recess gate structure is used during recess etch processing procedure 格罗方德半导体公司 2017-12-05 CN disclosed
CN-102816805-B Novel method for improving saccharic acid conversion rate of L-glutamic acid JILIN COFCO BIOCHEMICAL TECHNOLOGY CO LTD 2014-04-02 CN disclosed
CN-102816805-A Novel method for improving saccharic acid conversion rate of L-glutamic acid JILIN COFCO BIOCHEMICAL TECHNOLOGY CO LTD 2012-12-12 CN disclosed
CN-101508014-B Technological process capable reducing cross crack ratio of ferritic stainless steel continuous casting billet SHANXI TAIYUAN STEEL STAINLESS STEEL CO LTD 2012-01-18 CN disclosed
CN-101508014-A Technological process capable reducing cross crack ratio of ferritic stainless steel continuous casting billet SHANXI TAIYUAN STEEL STAINLESS (CN) 2009-08-19 CN disclosed