Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PKLR | P30613 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511014 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| SCHEMBL31317955 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| SCHEMBL30469515 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| SCHEMBL1412691 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| SCHEMBL29622863 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| Silver SCHEMBL2958255 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| SCHEMBL5068680 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| Water SCHEMBL28390010 | 0.94 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| Potassium Ion SCHEMBL2788338 | 0.94 | STAT3 (0.52) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 | |
| Potassium Ion SCHEMBL4797638 | 0.92 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959753-A | AN ELECTROLYTIC ELECTROCONDUCTIVE POLYMER DOPED WITH A NAPHTHALENE-OR ANTHRAQUINONESULFONATE ON A DIELECTRIC FILM FORMED FROM ANODIZING THE METAL SUBSTRATE; HEAT AND HUMIDITY RESISTANCE; SHELF LIFELEAK | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-09-25 | — | — | US | claimed |
| EP-0358239-A2 | Solid electrolytic capacitor and method of manufacturing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-03-14 | — | — | EP | claimed |
| CN-107442167-B | Catalyst for preparing aromatic polycarboxylic acid by liquid phase oxidation | 中国石油化工股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| EP-2218715-B1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | SUMITOMO SEIKA CHEMICALS (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-8216768-B2 | Photoacid generator and photoreactive composition | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100233621-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2218715-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | Sumitomo Seika Chemicals CO. LTD. (JP) | 2010-08-18 | — | — | EP | disclosed |
| WO-2002030906-A1 | ANTI-TUMOUR COMPOUNDS | LA TROBE UNIVERSITY (AU) | 2002-04-18 | — | — | WO | disclosed |
| US-5912386-A | Bridged anthraquinones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-15 | — | — | US | disclosed |
| US-4021455-A | Process for the manufacture of anthraquinonesulphonic acid | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-3971812-A | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233621-A1 | PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION | ARSA, SULT1A1, CYBA | ALDH1A1 261/4885SMN1; SMN2 4360/4885PKLR 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.