SCHEMBL29622863

SCHEMBL29622863

O=C1c2ccccc2C(=O)c2c1cccc2S(=O)(=O)[O-].[Na+]

nearest known ligand 0.59

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A known ✓ P29274 1/20 0.50
P2RY2 known ✓ P41231 1/20 0.46
P2RY1 known ✓ P47900 1/20 0.46
P2RY4 known ✓ P51582 1/20 0.46
P2RY6 known ✓ Q15077 1/20 0.46
P2RY12 known ✓ Q9H244 1/20 0.46
ALDH1A1 P00352 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
PKLR P30613 5/20 0.58
PTPN1 P18031 3/20 0.58
PGAM1 P18669 2/20 0.58
FTO Q9C0B1 1/20 0.51
STAT3 P40763 1/20 0.47
TTR P02766 1/20 0.46
MEN1 O00255 1/20 0.46
CDC25B P30305 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
EGFR P00533 2/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412691 1.00 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL31317955 1.00 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
Water SCHEMBL28390010 0.98 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
Potassium Ion SCHEMBL2787084 0.96 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL5068680 0.96 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
Silver SCHEMBL2958255 0.96 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL30469515 0.96 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL3511014 0.96 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL2786330 0.94 STAT3 (0.52) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1
SCHEMBL4794999 0.92 PKLR (0.49) ALDH1A1SMN1; SMN2PKLRPTPN1PGAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110697887-B Method for domesticating humic acid reducing bacteria based on humic acid reduction-denitrification coupling 天津大学 2022-05-13 CN claimed
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN disclosed
CN-117603001-A Method for selectively recovering toluene and amyl anthraquinone from alkaline cleaning wastewater 宜昌苏鹏科技有限公司 2024-02-27 CN disclosed
CN-116830036-A Two-component system 西托斯股份公司 2023-09-29 CN disclosed
CN-116830040-A Photopolymerizable compositions 西托斯股份公司 2023-09-29 CN disclosed