Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | ERN1 | O75460 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472288 | 0.88 | MAPT (0.37) | USP2LMNAMAPTHTT | |
| SCHEMBL472625 | 0.88 | LMNA (0.42) | USP2LMNAMAPTHTTAR | |
| SCHEMBL739419 | 0.86 | USP2 (0.32) | USP2LMNAMAPTHTT | |
| SCHEMBL472629 | 0.86 | MAPT (0.34) | USP2LMNAMAPTHTT | |
| SCHEMBL1864386 | 0.86 | TDP1 (0.35) | — | |
| Ammonia Solution, Strong SCHEMBL27964641 | 0.85 | MAPT (0.33) | USP2LMNAMAPTHTT | |
| SCHEMBL3116206 | 0.84 | VCAM1 (0.44) | USP2LMNAMAPTHTT | |
| SCHEMBL472676 | 0.84 | NCOA1 (0.33) | USP2LMNAMAPTHTT | |
| SCHEMBL737953 | 0.84 | NPC1 (0.35) | USP2LMNAMAPTHTTAR | |
| SCHEMBL1795659 | 0.84 | ALOX12 (0.33) | USP2MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |