Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1602216 | 0.89 | CDC25B (0.44) | CDC25BPTPN1PKMNEU3CA12 | |
| SCHEMBL17393220 | 0.83 | HIPK2 (0.44) | — | |
| SCHEMBL29365363 | 0.83 | PTPN1 (0.50) | CDC25BPTPN1PKMCA12CA1 | |
| SCHEMBL79524 | 0.83 | PTPN1 (0.50) | CDC25BPTPN1PKMCA12CA1 | |
| SCHEMBL1602825 | 0.82 | LCK (0.42) | CDC25BPKMCA12CA1CA2 | |
| SCHEMBL1724615 | 0.81 | NPSR1 (0.42) | CDC25BPTPN1PKMKDM4ETP53 | |
| SCHEMBL30014607 | 0.81 | NPSR1 (0.42) | CDC25BPTPN1PKMKDM4ETP53 | |
| SCHEMBL7941985 | 0.81 | PTPN1 (0.49) | CDC25BPTPN1PKMCA12CA1 | |
| SCHEMBL15387616 | 0.81 | PTPN1 (0.49) | CDC25BPTPN1PKMCA12CA1 | |
| SCHEMBL7944056 | 0.81 | PTPN1 (0.49) | CDC25BPTPN1PKMCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157343-A | Crystalline polyester resin, aqueous polyester resin dispersion, and adhesive or coating composition using same | 东洋纺MC株式会社 | 2023-12-01 | — | — | CN | disclosed |
| CN-115093595-B | laminated polyester film | 东洋纺株式会社 | 2023-11-17 | — | — | CN | disclosed |
| CN-111051404-B | Easy-to-adhere polyester film | 东洋纺株式会社 | 2023-09-22 | — | — | CN | disclosed |
| CN-115093595-A | Laminated polyester film | 东洋纺株式会社 | 2022-09-23 | — | — | CN | disclosed |
| CN-111051404-A | Easily adhesive polyester film | 东洋纺株式会社 | 2020-04-21 | — | — | CN | disclosed |
| CN-104520738-A | Polyester film for protecting polarizer, polarizing plate, and liquid crystal display device | TOYO BOSEKI | 2015-04-15 | — | — | CN | disclosed |