SCHEMBL1602216

SCHEMBL1602216

O=C(O)c1cc(S(=O)(=O)[O-])c2cc(C(=O)O)ccc2c1.[Na+]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 1/20 0.37
CA1 known ✓ P00915 1/20 0.37
CA2 known ✓ P00918 1/20 0.37
CDC25B P30305 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2C Q14957 1/20 0.43
PTPN1 P18031 1/20 0.42
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PLAU P00749 1/20 0.39
PKM P14618 1/20 0.39
PRMT1 Q99873 1/20 0.38
NEU3 Q9UQ49 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
HTT P42858 1/20 0.37
PLA2G2D Q9UNK4 1/20 0.37
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1724615 0.92 NPSR1 (0.42) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL30014607 0.92 NPSR1 (0.42) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL28009291 0.89 CDC25B (0.45) CDC25BPTPN1KDM4EKMT2APKM
SCHEMBL976104 0.85 CDC25B (0.47) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL29763597 0.85 CDC25B (0.47) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL1602825 0.84 LCK (0.42) CDC25BKDM4EMEN1KMT2APKM
SCHEMBL2964069 0.84 HIPK2 (0.47) CA1CA2
SCHEMBL1602218 0.83 CDC25B (0.46) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL7939204 0.83 CDC25B (0.46) CDC25BGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL7941298 0.83 CDC25B (0.46) CDC25BGRIN2DGRIN2AGRIN2CPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5106115-A None JP disclosed
EP-4748986-A1 CHENILLE YARN, FABRIC, AND CLOTHING PRODUCT Teijin Frontier Co., Ltd. (JP) 2026-05-27 EP disclosed
US-20250183478-A1 POLYAMIDE-IMIDE RESIN, POLYAMIDE-IMIDE FIBER, NONWOVEN FABRIC, AND SEPARATOR FOR ELECTRONIC COMPONENT TOYOBO MC CORPORATION (JP) 2025-06-05 US disclosed
WO-2025018376-A1 CHENILLE YARN, FABRIC, AND CLOTHING PRODUCT 帝人フロンティア株式会社 2025-01-23 WO disclosed
EP-4480980-A1 POLYAMIDIMIDE RESIN, POLYAMIDIMIDE FIBERS, NON-WOVEN FABRIC AND ELECTRONIC COMPONENT SEPARATOR TOYOBO MC Corporation (JP) 2024-12-25 EP disclosed
WO-2023157732-A1 POLYAMIDIMIDE RESIN, POLYAMIDIMIDE FIBERS, NON-WOVEN FABRIC AND ELECTRONIC COMPONENT SEPARATOR 東洋紡株式会社 2023-08-24 WO disclosed
EP-2492390-B1 POLYESTER FIBERS, PROCESS FOR PRODUCTION OF THE POLYESTER FIBERS, CLOTH, AND FIBER PRODUCT TEIJIN FRONTIER CO LTD (JP) 2018-06-06 EP disclosed
US-9334608-B2 Polyester fiber, method for producing the same, cloth, textile product, and polyester formed article TEIJIN FRONTIER CO., LTD. (JP) 2016-05-10 US disclosed
CN-102575414-B Polyester fiber and manufacture method, cloth and silk, fibre, polyester molded article TEIJIN FRONTIER Co.,Ltd. (JP) 2015-08-19 CN disclosed
EP-2492390-A1 POLYESTER FIBERS, PROCESS FOR PRODUCTION OF THE POLYESTER FIBERS, CLOTH, FIBER PRODUCT, AND POLYESTER MOLDED ARTICLE Teijin Fibers Limited (JP) 2012-08-29 EP disclosed
US-20060177655-A1 Polyether ester elastic fiber and fabric, clothes made by using the same TEIJIN FIBERS LIMITED (JP) 2006-08-10 US disclosed
CN-1809657-A Polyether ester elastic fiber and fabric and clothing using the same TEIJIN FIBERS LTD (JP) 2006-07-26 CN disclosed
EP-1643019-A1 POLYETHER ESTER ELASTIC FIBER AND FABRICS AND CLOTHES MADE BY USING THE SAME Teijin Fibers Limited (JP) 2006-04-05 EP disclosed
US-20050180999-A9 Cosmetic composition comprising interferential particles and a colouring material BLIN XAVIER (FR) 2005-08-18 US disclosed
US-20040076649-A1 Cosmetic composition with continuous lipophilic phase containing fibres L'OREAL S.A. (FR) 2004-04-22 US disclosed
US-20040076650-A1 Cosmetic composition comprising interferential particles and a colouring material BLIN XAVIER (FR) 2004-04-22 US disclosed
EP-0921217-B1 FIBER HAVING OPTICAL INTERFERENCE FUNCTION AND ITS UTILIZATION TEIJIN LTD (JP) 2003-12-03 EP disclosed
US-6430348-B1 FLAT; POLYMER ALTERNATING LAMINATED MULTILAYER TEIJIN LIMITED (JP) 2002-08-06 US disclosed
EP-0921217-A1 FIBER HAVING OPTICAL INTERFERENCE FUNCTION AND ITS UTILIZATION TEIJIN LIMITED (JP) 1999-06-09 EP disclosed
JP-H05106115-A MODIFIED POLYESTER FIBER TEIJIN LTD 1993-04-27 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040076649-A1 Cosmetic composition with continuous lipophilic phase containing fibres KRT18, CUTA, DSG1 CA12 2855/4885CA1 4301/4885CA2 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.