Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.52 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334357 | 1.00 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| Lindane SCHEMBL713825 | 0.89 | TET2 (0.43) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL18334377 | 0.84 | MAPT (0.56) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL18334378 | 0.84 | MAPT (0.56) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL22826568 | 0.82 | MAPT (0.59) | FOLH1MAPTLMNA | |
| SCHEMBL30816384 | 0.80 | MAPT (0.63) | MAPTLMNA | |
| SCHEMBL8639483 | 0.80 | MAPT (0.63) | MAPTLMNA | |
| SCHEMBL21443815 | 0.79 | GABRP (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL3510953 | 0.79 | KMT2A (0.56) | FOLH1CYP1A2GRM3GRM8GRM6 | |
| SCHEMBL25242218 | 0.77 | TET2 (0.41) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022196258-A1 | ONIUM SALT, PHOTOACID GENERATOR, COMPOSITION, AND METHOD FOR PRODUCING DEVICE USING SAME | 東洋合成工業株式会社 | 2022-09-22 | — | — | WO | disclosed |
| EP-3109230-B1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | LI QINGENG (CN) | 2019-11-20 | — | — | EP | disclosed |
| EP-3109229-B1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | JIANGSU NHWALUOKANG PHARMACEUTICAL RES AND DEVELOPMENT CO LTD (CN) | 2019-06-05 | — | — | EP | disclosed |
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | Li, Qingeng (CN) | 2019-03-26 | — | — | US | disclosed |
| CN-106029631-B | Carboxylic acid derivatives and application thereof in preparing prodrugs | 李勤耕 | 2018-12-28 | — | — | CN | disclosed |
| CN-106132922-B | A kind of water solubility propofol derivative and application thereof | 江苏恩华络康药物研发有限公司 | 2018-12-04 | — | — | CN | disclosed |
| US-9643917-B2 | Water-soluble propofol derivatives and uses thereof | JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD (CN) | 2017-05-09 | — | — | US | disclosed |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | LI, Qingeng (CN) | 2017-03-02 | — | — | US | disclosed |
| US-20170050920-A1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD (CN) | 2017-02-23 | — | — | US | disclosed |
| EP-3109230-A1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | Li, Qingeng (CN) | 2016-12-28 | — | — | EP | disclosed |
| CN-1678574-A | Process for producing aminoalkylsulfonic acid and method of salt exchange for salt thereof | WAKO PURE CHEM IND LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| EP-0914942-B1 | Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates | TORAY INDUSTRIES (JP) | 2005-05-25 | — | — | EP | disclosed |
| EP-1481802-A1 | Directly imageable planographic printing plate precursor and a method of producing planographic printing plate | TORAY INDUSTRIES, INC. (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1046496-B1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-6420083-B1 | EXCELLENT SENSITIVITY; DOES NOT REQUIRE WET DEVELOPMENT; HYDROPHILIC GROUPS IN POLYMER COORDINATE WITH THE POLYVALENT METAL CATION RELEASED BY HEAT AND FORM A HYDROPHOBIC POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1046496-A1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0914942-A2 | Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates | TORAY INDUSTRIES, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |
| EP-0327070-B1 | FLUOROCARBON CHAIN-CONTAINING ANTIGENIC CONJUGATES | BIOMIRA, INC. (CA) | 1993-05-05 | — | — | EP | disclosed |
| US-5055562-A | Haptens linked to protein carriers | BIOMIRA, INC. (CA) | 1991-10-08 | — | — | US | disclosed |
| EP-0327070-A1 | Fluorocarbon chain-containing antigenic conjugates | BIOMIRA, INC. (CA) | 1989-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | NR4A3, HCAR3, FFAR3 | TET2 2744/4885KDM4A 1179/4885KDM4C 2125/4885 |
| US-20170050920-A1 | WATER-SOLUBLE PROPOFOL DERIVATIVES AND USES THEREOF | OPRM1, OPRD1, SIGMAR1 | TET2 660/4885KDM4A 2602/4885KDM4C 3549/4885 |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | NR4A3, HCAR3, NR4A2 | TET2 2604/4885KDM4A 1044/4885KDM4C 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.