Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041359 | 0.77 | DPP4 (0.39) | DPP4PNMTHTR2A | |
| Hydrochloric Acid SCHEMBL4089006 | 0.76 | CHRNB2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL28041358 | 0.75 | HTR7 (0.35) | PNMT | |
| Fluoride Ion SCHEMBL5183964 | 0.72 | CHRNB2 (0.35) | — | |
| Bromide SCHEMBL27477694 | 0.72 | CHRNB2 (0.35) | — | |
| SCHEMBL3787333 | 0.70 | DPP4 (0.73) | DPP4PNMTHTR2A | |
| Hydrochloric Acid SCHEMBL9440329 | 0.66 | CYP1A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7058361 | 0.65 | HTR1A (0.37) | — | |
| SCHEMBL28030816 | 0.65 | DPP4 (0.46) | DPP4PNMT | |
| Hydrochloric Acid SCHEMBL4083401 | 0.64 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026408-A | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORP | 2015-11-04 | — | — | CN | disclosed |