Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27648778 | 0.88 | NCF1 (0.45) | ADRB2NCF1HTR6HTR3AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28761806 | 0.87 | NCF1 (0.44) | ADRB2NCF1HTR6HTR3AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28302827 | 0.86 | ALDH1A1 (0.52) | ADRB2NCF1HTR6HTR3AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28042680 | 0.81 | DRD2 (0.40) | HTR6HTR3AALDH1A1HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL27981819 | 0.80 | MAOB (0.55) | ADRB2NCF1HTR6HTR3AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27974539 | 0.80 | ADRB1 (0.47) | NCF1HTR6HTR3AHTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28112740 | 0.79 | HTR1A (0.48) | ADRB2NCF1HTR6HTR3AHTR2C | |
| Tert-Butyl Formate SCHEMBL28042825 | 0.79 | NCF1 (0.45) | ADRB2NCF1HTR6HTR3AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27588079 | 0.78 | HTR5A (0.41) | HTR6HTR3AALDH1A1HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28001276 | 0.78 | MGLL (0.43) | ADRB2NCF1HTR6MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105294554-A | Phenylpiperazine derivative, use method and uses thereof | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG DRUG TRADING CO LTD | 2016-02-03 | — | — | CN | disclosed |