Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053242 | 0.78 | APLNR (0.43) | SCN10AAPLNRCA1CA2CA9 | |
| SCHEMBL28053258 | 0.76 | PKM (0.46) | ALDH1A1GAAMAPTAPLNRGCK | |
| SCHEMBL28826183 | 0.75 | APLNR (0.40) | APLNRCA12CA1CA2CA9 | |
| SCHEMBL28053239 | 0.73 | APLNR (0.38) | ALDH1A1APLNRCA12CA1CA2 | |
| SCHEMBL16235625 | 0.73 | ALDH1A1 (0.42) | SCN10AALDH1A1GAAMAPT | |
| SCHEMBL28053322 | 0.72 | APLNR (0.51) | ALDH1A1APLNRCA12CA1CA2 | |
| SCHEMBL28826194 | 0.70 | SOS1 (0.39) | MAPTAPLNRCA12CA1CA2 | |
| SCHEMBL28053374 | 0.70 | LRRK2 (0.44) | APLNRCA12CA1CA2CA9 | |
| SCHEMBL28053327 | 0.70 | APLNR (0.45) | APLNRCA12CA1CA2CA9 | |
| SCHEMBL16235343 | 0.69 | ALDH1A1 (0.38) | ALDH1A1GAAMAPTGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | claimed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |