Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA9 | Q16790 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053374 | 0.87 | LRRK2 (0.44) | TDP2NSD2HK1PAX8CA1 | |
| SCHEMBL28053244 | 0.81 | RORC (0.44) | CA1CA2CA9PTGS1PTGS2 | |
| SCHEMBL28053242 | 0.79 | APLNR (0.43) | CA1CA2CA9APLNRPTGS1 | |
| SCHEMBL28053327 | 0.79 | APLNR (0.45) | POLBCA1CA2CA9CA12 | |
| SCHEMBL28053322 | 0.78 | APLNR (0.51) | POLBALDH1A1CA1CA2CA9 | |
| SCHEMBL28826183 | 0.76 | APLNR (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28053310 | 0.76 | SCN10A (0.44) | ALDH1A1GAAMAPTCA1CA2 | |
| SCHEMBL28826194 | 0.74 | SOS1 (0.39) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL28053239 | 0.74 | APLNR (0.38) | POLBALDH1A1CA1CA2CA9 | |
| SCHEMBL28053341 | 0.73 | PKM (0.49) | PKMPOLBALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |