Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064182 | 0.91 | LTA4H (0.36) | LTA4HSLC6A3KCNA5 | |
| SCHEMBL28064062 | 0.87 | RAB9A (0.39) | RAB9ANPC1HPGDKMT2AMEN1 | |
| SCHEMBL27884721 | 0.79 | MMP2 (0.43) | RAB9ANPC1HPGDKMT2AMEN1 | |
| SCHEMBL28827928 | 0.79 | MEN1 (0.39) | KMT2AMEN1LTA4HSLC6A3 | |
| SCHEMBL28064078 | 0.76 | TEAD1 (0.45) | ALDH1A1LTA4HLMNA | |
| SCHEMBL28064080 | 0.76 | HRH3 (0.39) | HPGDLTA4HLMNAHRH3KCNH2 | |
| SCHEMBL28946451 | 0.72 | MMP2 (0.43) | RAB9AKMT2AMEN1ALDH1A1LTA4H | |
| SCHEMBL28064071 | 0.71 | ALDH1A1 (0.38) | RAB9ANPC1HPGDKMT2AMEN1 | |
| SCHEMBL9382209 | 0.71 | SLC6A3 (0.48) | RAB9ANPC1KMT2AALDH1A1GRM5 | |
| SCHEMBL28064082 | 0.70 | KDM4E (0.41) | KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |