Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064086 | 0.86 | LTA4H (0.39) | HCRTR1HCRTR2LTA4HPARP15PARP10 | |
| SCHEMBL28827929 | 0.83 | ALDH1A1 (0.39) | HCRTR1HCRTR2LTA4HMEN1POLB | |
| SCHEMBL27884632 | 0.80 | PARP15 (0.39) | HCRTR1HCRTR2LTA4HPARP15PARP10 | |
| SCHEMBL28064060 | 0.77 | LTA4H (0.39) | LTA4HPARP15PARP10MEN1KMT2A | |
| SCHEMBL28064084 | 0.76 | TEAD1 (0.47) | LTA4HPARP15PARP10 | |
| SCHEMBL28064087 | 0.75 | TEAD1 (0.44) | LTA4HPARP15PARP10 | |
| SCHEMBL28064068 | 0.75 | PARP10 (0.53) | LTA4HPARP15PARP10 | |
| SCHEMBL2227860 | 0.75 | GRIN2B (0.47) | LTA4HPARP15PARP10MEN1POLB | |
| SCHEMBL28064070 | 0.75 | LTA4H (0.39) | LTA4HPARP15PARP10 | |
| SCHEMBL28088153 | 0.73 | HRH3 (0.37) | HCRTR1HCRTR2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |