Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768486 | 0.84 | KMT2A (0.57) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL1948795 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1MAPTTDP1NPC1 | |
| SCHEMBL1948655 | 0.80 | CA12 (0.50) | MAPK1SMN1; SMN2PPARGPPARACA12 | |
| SCHEMBL11910716 | 0.78 | KMT2A (0.50) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL3218996 | 0.78 | L3MBTL1 (0.42) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL3786555 | 0.78 | TDP1 (0.50) | KMT2ATDP1PPARGPPARACA12 | |
| SCHEMBL941121 | 0.76 | JAK3 (0.48) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL27316994 | 0.76 | MAPT (0.55) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL17844769 | 0.75 | ADRB2 (0.49) | KMT2AMAPK1SMN1; SMN2TDP1CA12 | |
| SCHEMBL28829142 | 0.75 | CTSK (0.45) | MAPTPPARGPPARAPPARDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867630-A | - 1 receptor modulators of novel glp-1 | 赛尔基因第二国际有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-105593225-B | novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105593225-A | Novel GLP-1 receptor modulators | RECEPTOS INC | 2016-05-18 | — | — | CN | disclosed |