SCHEMBL28080830

SCHEMBL28080830

COc1cc(Cn2cc(-c3ccccc3)c(-c3ccccc3)c2C(=O)C=O)cc(OC)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 13/20 0.46
TUBB P07437 13/20 0.46
TUBA3C P0DPH7 13/20 0.46
TUBA1B P68363 13/20 0.46
TUBA4A P68366 13/20 0.46
TUBB4B P68371 13/20 0.46
TUBB3 Q13509 13/20 0.46
TUBB2A Q13885 13/20 0.46
TUBB8 Q3ZCM7 13/20 0.46
TUBA3E Q6PEY2 13/20 0.46
TUBA1A Q71U36 13/20 0.46
TUBA1C Q9BQE3 13/20 0.46
TUBB6 Q9BUF5 13/20 0.46
TUBB2B Q9BVA1 13/20 0.46
TUBB1 Q9H4B7 13/20 0.46
POLB P06746 1/20 0.44
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28080844 0.90 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27962498 0.88 ICMT (0.43) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27962503 0.85 PTAFR (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28080966 0.83 GFER (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28080836 0.82 F2RL3 (0.39) ALDH1A1
SCHEMBL28080903 0.78 ALDH1A1 (0.43) POLBALDH1A1MEN1KMT2A
SCHEMBL28080894 0.76 ALDH1A1 (0.47) ALDH1A1
SCHEMBL28080828 0.76 CCR2 (0.46) CYP3A4CYP2C9MEN1KMT2A
SCHEMBL28080843 0.74 CYP11B1 (0.44) POLBALDH1A1
Benzene SCHEMBL28080834 0.72 CNR2 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103804108-B A kind of method preparing primary amine 沈阳药科大学 2016-08-03 CN disclosed