Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.76 |
| ▸ | CA4 | P22748 | 2/20 | 0.76 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL3667327 | 0.90 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11789341 | 0.89 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL5072459 | 0.87 | CA2 (0.80) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL158696 | 0.87 | CA2 (0.80) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29624 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL579255 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL457494 | 0.87 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994012115-A1 | PROTECTIVE MEDICAL GLOVE AND ANTIBACTERIAL/ANTIPERSPIRANT COMPOSITION FOR REDUCING BACTERIAL GROWTH DURING USE OF MEDICAL GLOVES | BUCHANAN, INC. (US) | 1994-06-09 | — | — | WO | claimed |
| US-12564558-B2 | Hybrid exosomal-polymeric (hexpo) nano-platform for delivery of RNAi therapeutics | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-03-03 | — | — | US | disclosed |
| EP-3592329-B1 | USE OF COMPATIBLE SOLUTES | SUSONITY Commercial GmbH (DE) | 2026-02-18 | — | — | EP | disclosed |
| EP-4007561-B1 | PREVENTION AND REDUCTION OF CORNIFICATION DISORDERS AND RELATED COSMETIC AGENTS | MERCK PATENT GMBH (DE) | 2025-08-27 | — | — | EP | disclosed |
| CN-119923247-A | Compositions with improved SPF and UVA photoprotection | 西姆莱斯股份公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119744164-A | Odor and colorant stable compositions | 西姆莱斯股份公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119604270-A | Comprising an antimicrobial agent accelerator composition | 西姆莱斯股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119604267-A | Compositions with improved SPF and UVA photoprotection | 西姆莱斯股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119584951-A | Composition comprising a UV filter stabilizer | 西姆莱斯股份公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-118591292-A | Antimicrobial liquid compositions, methods of making antimicrobial liquid compositions, and methods of use thereof | 埃斯普投资有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-4347330-A | OPEN-CELL POLYURETHANE FOAM; POLYSILOXANE-POLYOXYALKYLENE, POLYMETHYLSILOXANE, POLYOXYETHYLENE POLYETHER CELL MODIFIERS | BASF WYANDOTTE CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-4324799-A | Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4324867-A | FROM A POLYETHER, ISOCYANATE, DIAMINODIPHENYLALKANE MIXTURE | BASF WYANDOTTE CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
| EP-0045413-A1 | Flexible polyurethane foam compositions and methods for the preparation | BASF WYANDOTTE CORPORATION (US) | 1982-02-10 | — | — | EP | disclosed |
| US-4232127-A | POLYMERIZATION CATALYSTS, CONDENSATION POLYMERIZATION | BASF WYANDOTTE CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4210728-A | Preparation of high resiliency polyurethane foams | BASF WYANDOTTE CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4038071-A | REDUCTION OF ION TO FREE METAL, PRECIPITATION | TENNECO CHEMICALS, INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3994839-A | Urethane modified carbodiimide foams derived from flame retardant polyols | BASF WYANDOTTE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3959149-A | Isocyanate resin absorbent for free chlorine, heavy metals and heavy metallic compounds | NIPPON SODA COMPANY LIMITED (JA) | 1976-05-25 | — | — | US | disclosed |
| US-3932509-A | FUNGICIDES, VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564558-B2 | Hybrid exosomal-polymeric (hexpo) nano-platform for delivery of RNAi therapeutics | EXOSC5, EXOSC9, EXOSC10 | CA2 4243/4885CA4 3097/4885CES1 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.