Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103538 | 0.88 | NCF1 (0.38) | ALOX5 | |
| SCHEMBL28103279 | 0.80 | ALOX5 (0.46) | ALOX5DRD2DRD3MAPTTSHR | |
| SCHEMBL28103546 | 0.80 | MGLL (0.35) | MGLLHCAR1 | |
| SCHEMBL28103584 | 0.79 | FAAH (0.40) | DRD2HTR1AMAPTMGLLHCAR1 | |
| SCHEMBL28103298 | 0.79 | DRD2 (0.48) | DRD2DRD3LMNAMAPTMEN1 | |
| SCHEMBL28103613 | 0.76 | MGLL (0.37) | HTR2AHTR2CLMNAMAPTMEN1 | |
| SCHEMBL27671224 | 0.76 | ALOX5 (0.41) | ALOX5MEN1KMT2AGAA | |
| SCHEMBL28103609 | 0.72 | NOTUM (0.38) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL27380663 | 0.67 | ALOX5 (0.44) | ALOX5MEN1KMT2A | |
| SCHEMBL28835067 | 0.67 | ALOX5 (0.49) | ALOX5DRD2MAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |