Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DCTPP1 | Q9H773 | 8/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111329 | 0.80 | DCTPP1 (0.65) | TP53DCTPP1SCDMMP13 | |
| SCHEMBL28111733 | 0.77 | MMP13 (0.52) | MMP13ALDH1A1KMT2AHPGDGLA | |
| SCHEMBL28111776 | 0.72 | MAPT (0.64) | MMP13ALDH1A1KMT2AHPGD | |
| SCHEMBL27936850 | 0.70 | KMT2A (0.61) | TP53ALDH1A1KMT2AHPGD | |
| SCHEMBL13528347 | 0.69 | KMT2A (0.52) | TP53PRKAA2ALDH1A1KMT2AHPGD | |
| SCHEMBL28836629 | 0.69 | VNN1 (0.56) | MMP13KMT2AHPGD | |
| SCHEMBL28111205 | 0.68 | DCTPP1 (0.63) | DCTPP1SCDPRKAA2 | |
| SCHEMBL3231445 | 0.68 | MMP13 (0.67) | TP53MMP13ALDH1A1KMT2A | |
| SCHEMBL28111232 | 0.68 | HTT (0.58) | MMP13ALDH1A1KMT2AHPGDPOLB | |
| SCHEMBL6559744 | 0.67 | KDM4E (0.68) | TP53ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |