SCHEMBL2811179

SCHEMBL2811179

CC(N)C(=O)NC(CCCNC(=N)N)C(=O)O.[Cu]

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 3/20 0.51
NPY4R P50391 14/20 0.43
NPY1R P25929 9/20 0.43
NPY5R Q15761 8/20 0.43
NPY2R P49146 5/20 0.43
FOLH1 Q04609 1/20 0.39
GNPAT O15228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490761 0.99 NOD1 (0.52) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL29787128 0.99 NOD1 (0.52) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL29697052 0.99 NOD1 (0.52) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL5598692 0.99 NOD1 (0.52) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL31454130 0.99 NOD1 (0.52) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL4587351 0.97 NOD1 (0.51) NOD1NPY4RNPY1RNPY5RNPY2R
Hydrochloric Acid SCHEMBL9186802 0.97 NOD1 (0.51) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL23286096 0.96 NOD1 (0.50) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL1711604 0.96 NOD1 (0.50) NOD1NPY4RNPY1RNPY5RNPY2R
SCHEMBL1711608 0.96 NOD1 (0.50) NOD1NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 NOD1 2084/4885NPY4R 811/4885NPY1R 171/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC NOD1 4126/4885NPY4R 1065/4885NPY1R 269/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 NOD1 4770/4885NPY4R 785/4885NPY1R 300/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 NOD1 3796/4885NPY4R 797/4885NPY1R 936/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC NOD1 2576/4885NPY4R 496/4885NPY1R 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.