SCHEMBL2812795

SCHEMBL2812795

Cc1[nH]cnc1C[C@H](NC(=O)[C@H](C)N)C(=O)[O-].Cc1[nH]cnc1C[C@H](NC(=O)[C@H](C)N)C(=O)[O-].[Cu+2]

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.41
HRH2 P25021 1/20 0.37
HRH1 P35367 1/20 0.37
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CAPN1 P07384 1/20 0.35
XIAP P98170 1/20 0.35
FDPS P14324 1/20 0.35
WDR5 P61964 4/20 0.34
KMT2A Q03164 4/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
CTRB1 P17538 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4589240 0.97 GABRR1 (0.41) GABRR1HRH2HRH1HRH4HRH3
SCHEMBL7806464 0.89 CTRB1 (0.43) TDP1WDR5KMT2ACTSLCTSS
SCHEMBL5598732 0.87 GABRR1 (0.47) GABRR1HRH2HRH1HRH4HRH3
SCHEMBL2241941 0.87 SLC15A2 (0.43) GABRR1HRH2HRH1HRH4HRH3
SCHEMBL2813443 0.84 GABRR1 (0.42) GABRR1HRH2HRH1HRH4HRH3
SCHEMBL9082649 0.82 SLC15A2 (0.35) WDR5KMT2A
SCHEMBL4588631 0.81 GABRR1 (0.42) GABRR1HRH2HRH1HRH4HRH3
SCHEMBL30002169 0.78 MME (0.46) WDR5KMT2ACTRB1
SCHEMBL5598811 0.78 SLC15A2 (0.52) GABRR1
SCHEMBL27842689 0.78 FNTA (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 GABRR1 677/4885HRH2 56/4885HRH1 19/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC GABRR1 1878/4885HRH2 2095/4885HRH1 1410/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 GABRR1 1368/4885HRH2 1100/4885HRH1 766/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 GABRR1 2721/4885HRH2 2117/4885HRH1 873/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC GABRR1 3116/4885HRH2 2039/4885HRH1 1200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.