SCHEMBL2815390

SCHEMBL2815390

NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N[C@H]([C]=O)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.49
▸ STAT6 P42226 1/20 0.46
▸ C5AR1 P21730 2/20 0.45
▸ ACE P12821 2/20 0.44
▸ OPRM1 P35372 6/20 0.44
▸ OPRK1 P41145 6/20 0.44
▸ APLNR P35414 1/20 0.44
▸ REN P00797 3/20 0.43
▸ MC4R P32245 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30002373 0.90 ACE (0.53) F2STAT6C5AR1ACEOPRM1
SCHEMBL5969903 0.90 ACE (0.53) F2STAT6C5AR1ACEOPRM1
SCHEMBL5969907 0.89 F2 (0.52) F2STAT6C5AR1ACEOPRM1
SCHEMBL8953877 0.86 C5AR1 (0.55) F2C5AR1APLNRREN
SCHEMBL9642162 0.86 NTSR2 (0.43) F2C5AR1OPRM1OPRK1APLNR
SCHEMBL10622567 0.86 C5AR1 (0.54) F2C5AR1APLNRREN
SCHEMBL8953791 0.86 C5AR1 (0.52) F2C5AR1ACEAPLNRREN
SCHEMBL2814077 0.85 SLC15A2 (0.47) —
SCHEMBL2354522 0.85 SLC15A2 (0.46) —
SCHEMBL2354514 0.85 SLC15A2 (0.46) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 — — US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 — — EP disclosed
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN PROCYTE CORPORATION (US) 2008-10-16 — — US disclosed
US-7384916-B2 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2008-06-10 — — US disclosed
US-7186687-B2 Compositions and methods for treatment of Psoriasis PROCYTE CORPORATION (US) 2007-03-06 — — US disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 — — US disclosed
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2006-11-02 — — US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 — — US disclosed
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin PROCYTE CORPORATION (US) 2006-01-26 — — US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 — — US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 — — US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin RBP1, RBP4, SOD1 F2 3775/4885STAT6 2852/4885C5AR1 3034/4885
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin RBP1, RBP4, MC1R F2 3573/4885STAT6 1913/4885C5AR1 2439/4885
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 F2 847/4885STAT6 738/4885C5AR1 238/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 F2 1511/4885STAT6 2390/4885C5AR1 1684/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 F2 603/4885STAT6 18/4885C5AR1 277/4885
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN RBP1, RBP4, SOD1 F2 3775/4885STAT6 2852/4885C5AR1 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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