Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12843804 | 0.80 | CA2 (0.33) | FFAR1SLC22A12CA12CA1CA7 | |
| SCHEMBL13397789 | 0.80 | HDAC4 (0.47) | ALDH1A1 | |
| SCHEMBL4958265 | 0.78 | TDP1 (0.41) | ALDH1A1KMT2A | |
| Benzene SCHEMBL4958274 | 0.78 | LMNA (0.50) | CA12CA1CA4CA7CSNK2A2 | |
| SCHEMBL10328403 | 0.76 | UGT2B7 (0.46) | CA12CA1CA4CA7ALDH1A1 | |
| SCHEMBL11436231 | 0.76 | LMNA (0.52) | CA1ALDH1A1 | |
| SCHEMBL433935 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA4CA7ALDH1A1 | |
| SCHEMBL9516526 | 0.76 | FOLH1 (0.46) | KMT2A | |
| SCHEMBL28261238 | 0.75 | FFAR1 (0.51) | FFAR1S1PR1S1PR3S1PR5IDO1 | |
| SCHEMBL15511869 | 0.73 | TDP1 (0.45) | CYP2C9CA12CA1CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100304381-A1 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | Life Technologies Corporation (US) | 2010-12-02 | — | — | US | disclosed |
| US-7687236-B2 | Fluorescent nucleobase conjugates having anionic linkers | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1317464-B1 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | APPLERA CORP (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20090092986-A1 | Fluorescent Nucleobase Conjugates Having Anionic Linkers | APPLIED BIOSYSTEMS INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-7429651-B2 | Fluorescent nucleobase conjugates having anionic linkers | APPLERA CORPORATION (US) | 2008-09-30 | — | — | US | disclosed |
| US-20070254298-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2007-11-01 | — | — | US | disclosed |
| US-20060188915-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION (US) | 2006-08-24 | — | — | US | disclosed |
| US-7038063-B2 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | APPLERA CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050250119-A1 | Fluorescent nucleobase conjugates having anionic linkers | APPLERA CORPORATION (US) | 2005-11-10 | — | — | US | disclosed |
| US-20040229235-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | APPLERA CORPORATION | 2004-11-18 | — | — | US | disclosed |
| US-6811979-B2 | NUCLEOTIDE DERIVATIVE FOR USE IN SEQUENCE DETERMINATION OF NUCLEIC ACID MOLECULE | APPLERA CORPORATION | 2004-11-02 | — | — | US | disclosed |
| US-6649769-B2 | For labelling a polynucleotides | APPLERA CORPORATION | 2003-11-18 | — | — | US | disclosed |
| EP-1330550-A2 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | Applera Corporation (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-1317464-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | Applera Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20030055243-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | PE CORPORATION (NY) | 2003-03-20 | — | — | US | disclosed |
| US-6448407-B1 | LABELS FOR SUCH AS NUCLEOTIDES, NUCLEOSIDES, POLYPEPTIDES, POLYNUCLEOTIDES AND CARBOHYDRATES; SEQUENCING, FRAGMENT ANALYSIS, OLIGONUCLEOTIDE LIGATION, AMPLIFICATION, MINISEQUENCING, AND PRIMER EXTENSION | PE CORPORATION (NY) | 2002-09-10 | — | — | US | disclosed |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | PE CORPORATION (NY) (US) | 2002-08-01 | — | — | US | disclosed |
| WO-2002036832-A2 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002030944-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | APPLERA CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060188915-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | CHRNB3, CHRNB4, SPR | FFAR1 1543/4885SLC22A12 1001/4885CYP2C9 1550/4885 |
| US-20070254298-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS | CHRNB3, CHRNB4, SPR | FFAR1 1535/4885SLC22A12 1065/4885CYP2C9 1442/4885 |
| US-20050250119-A1 | Fluorescent nucleobase conjugates having anionic linkers | DNTT, DUT, NT5C3B | FFAR1 2477/4885SLC22A12 678/4885CYP2C9 3930/4885 |
| US-20040229235-A1 | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis | CHRNB3, CHRNB4, SPR | FFAR1 1543/4885SLC22A12 1001/4885CYP2C9 1550/4885 |
| US-20100304381-A1 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | DNTT, DUT, NT5C3B | FFAR1 2477/4885SLC22A12 678/4885CYP2C9 3930/4885 |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | DNTT, DUT, NT5C3B | FFAR1 2477/4885SLC22A12 678/4885CYP2C9 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.