SCHEMBL2822149

SCHEMBL2822149

Cc1ccc(S(=O)(=O)OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.45
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA5A P35218 2/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
DNMT1 P26358 1/20 0.41
VDR P11473 1/20 0.41
BCHE P06276 3/20 0.41
ACHE P22303 3/20 0.41
TLR9 Q9NR96 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL5227834 0.93 GAA (0.40) GAACA1CA2CA5ACA9
SCHEMBL36225 0.85 GAA (0.45) GAACA1CA2CA5ACA9
SCHEMBL562051 0.83 GAA (0.43) GAACA1CA2CA5ACA9
SCHEMBL28963307 0.83 GAA (0.43) GAACA1CA2CA5ACA9
SCHEMBL8847449 0.82 HTR6 (0.42) CA1CA2CA5ACA9CA12
SCHEMBL31349717 0.81 GAA (0.42) GAACA1CA2CA5ACA9
SCHEMBL28500294 0.81 ALDH1A1 (0.42) GAACA1CA2CA5ACA9
SCHEMBL9418423 0.81 PKM (0.52) GAACA1CA2SMN1; SMN2KMT2A
SCHEMBL6490 0.81 GAA (0.59) GAACA1CA2CA5ACA9
SCHEMBL9418416 0.81 TDP1 (0.46) GAACA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11707538-B2 Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides WASHINGTON UNIVERSITY (US) 2023-07-25 US claimed
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride WASHINGTON UNIVERSITY (US) 2022-02-08 US claimed
CN-113735813-A Photocatalytic synthesis method of 3-trifluoromethylselenocyclochromone compound 湖南科技学院 2021-12-03 CN claimed
US-20200197422-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. 2020-06-25 US claimed
CN-111233869-A Novel compound for preparing Rudexilvir key intermediate and preparation method thereof 杭州新博思生物医药有限公司 2020-06-05 CN claimed
US-5905163-A REDUCTION OF CYANO GROUP BY CATALYTIC HYDROGENATION MONSANTO COMPANY (US) 1999-05-18 US claimed
EP-4591935-A2 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2025-07-30 EP disclosed
CN-113549120-B Method for preparing ribonucleoside 吉利德科学公司 2025-04-29 CN disclosed
EP-4036099-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2025-03-19 EP disclosed
US-20240409575-A1 METHODS OF PREPARING 1'-CYANO NUCLEOSIDES GILEAD SCIENCES, INC. 2024-12-12 US disclosed
CN-118994170-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-11-22 CN disclosed
CN-118812607-A Method for preparing ribonucleoside 吉利德科学公司 2024-10-22 CN disclosed
CN-115298181-B Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-08-16 CN disclosed
CN-1290275-A Catalyst and process for polymerization of cycloolefin GOODRICH CO B F (US) 2001-04-04 CN disclosed
US-5905163-A REDUCTION OF CYANO GROUP BY CATALYTIC HYDROGENATION MONSANTO COMPANY (US) 1999-05-18 US disclosed
EP-0546056-B1 MEMBRANES HAVING SELECTIVE PERMEABILITY UNIV CALIFORNIA (US) 1996-04-24 EP disclosed
US-5358556-A Separation of gas mixtures THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-10-25 US disclosed
EP-0546056-A1 MEMBRANES HAVING SELECTIVE PERMEABILITY. UNIV CALIFORNIA (US) 1993-06-16 EP disclosed
US-5096586-A Doped and undoped with acids and bases REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-03-17 US disclosed
WO-1992003217-A1 MEMBRANES HAVING SELECTIVE PERMEABILITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409575-A1 METHODS OF PREPARING 1'-CYANO NUCLEOSIDES PNP, TYMP, DUT GAA 271/4885CA1 2424/4885CA2 2966/4885
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride STX18, GPR119, SLC5A1 GAA 268/4885CA1 881/4885CA2 818/4885
US-11707538-B2 Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides STX18, PFAS, FLI1 GAA 142/4885CA1 1601/4885CA2 1542/4885
US-20200197422-A1 METHODS FOR THE PREPARATION OF RIBOSIDES PRPS1, PRPF4, PRPF31 GAA 343/4885CA1 4736/4885CA2 4682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.