Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822997 | 0.83 | L3MBTL1 (0.33) | ALDH1A1 | |
| SCHEMBL2823122 | 0.81 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDATM | |
| SCHEMBL2819564 | 0.75 | PTGS2 (0.37) | ALDH1A1HPGD | |
| SCHEMBL2820524 | 0.74 | GCGR (0.33) | — | |
| SCHEMBL2819998 | 0.73 | P2RX7 (0.32) | ALDH1A1HPGD | |
| SCHEMBL2820005 | 0.73 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGD | |
| SCHEMBL2823211 | 0.72 | LMNA (0.38) | KDM4EALDH1A1HPGD | |
| SCHEMBL2819557 | 0.71 | HTT (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL2823560 | 0.70 | KMT2A (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL2850066 | 0.69 | PLA2G2A (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |