Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.47 |
| ▸ | KIF11 | P52732 | 10/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28242134 | 0.78 | FAAH (0.46) | FAAHKMO | |
| SCHEMBL16538344 | 0.76 | KIF11 (0.42) | KIF11FAAH | |
| SCHEMBL28242165 | 0.75 | CYP11B2 (0.52) | CYP11B2CYP11B1KIF11FAAHKMO | |
| SCHEMBL6184163 | 0.74 | KMO (0.52) | FAAHKMO | |
| SCHEMBL16635221 | 0.74 | CYP11B2 (0.58) | CYP11B2CYP11B1KIF11FAAHKMO | |
| SCHEMBL1202858 | 0.73 | RAB9A (0.36) | FAAH | |
| SCHEMBL8303859 | 0.72 | KDM1A (0.37) | KMO | |
| SCHEMBL28074571 | 0.72 | TRPV4 (0.42) | — | |
| SCHEMBL21116892 | 0.72 | KIF11 (0.76) | CYP11B2CYP11B1KIF11 | |
| SCHEMBL16635456 | 0.71 | FAAH (0.49) | CYP11B2CYP11B1KIF11FAAHKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612153-B | Substituted heterocyclic sulfonamide compound as TRPA1 conditioning agents | 豪夫迈·罗氏有限公司 | 2018-09-14 | — | — | CN | disclosed |