Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184163 | 0.83 | KMO (0.52) | KDM1AKMOCTSSCTSKTDP1 | |
| SCHEMBL16538344 | 0.82 | KIF11 (0.42) | KDM1AABL1BCR | |
| SCHEMBL28074640 | 0.72 | NPSR1 (0.40) | KDM1AKDM4EALDH1A1 | |
| SCHEMBL28242166 | 0.72 | CYP11B2 (0.47) | KMO | |
| SCHEMBL3998445 | 0.71 | SMN1; SMN2 (0.38) | KDM1AKMOCTSSCTSKF2RL3 | |
| SCHEMBL28074571 | 0.71 | TRPV4 (0.42) | ABL1BCR | |
| SCHEMBL1202858 | 0.68 | RAB9A (0.36) | KDM4EALDH1A1 | |
| SCHEMBL28074503 | 0.68 | SCN5A (0.43) | ABL1BCRKDM4EALDH1A1 | |
| SCHEMBL28790265 | 0.67 | KMO (0.49) | KMOKDM4E | |
| SCHEMBL28242134 | 0.66 | FAAH (0.46) | KMOCTSKABL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937051-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020003-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |