SCHEMBL28244569

SCHEMBL28244569

CC1=NN(c2ccc(S(=O)(=O)[O-])cc2)C(=O)C1N=Nc1ccc(C(c2ccccc2)c2ccc(N=NC3C(=O)N(c4ccc(S(=O)(=O)[O-])cc4)N=C3C)cc2)cc1.[Na+].[Na+]

nearest known ligand 0.66

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 14/20 0.66
▸ KMT2A Q03164 14/20 0.66
▸ MAPT P10636 10/20 0.66
▸ CYP1A2 P05177 2/20 0.66
▸ GAA P10253 2/20 0.66
▸ ALDH1A1 P00352 6/20 0.61
▸ NPC1 O15118 6/20 0.61
▸ RAB9A P51151 5/20 0.61
▸ SMN1; SMN2 Q16637 4/20 0.61
▸ LMNA P02545 4/20 0.61
▸ MAPK1 P28482 3/20 0.61
▸ TDP1 Q9NUW8 2/20 0.61
▸ POLB P06746 3/20 0.59
▸ KDM4E B2RXH2 2/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ ATM Q13315 1/20 0.57
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ CASP3 P42574 2/20 0.42
▸ SENP7 Q9BQF6 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31152951 0.91 MEN1 (0.79) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL342266 0.91 MAPT (0.75) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL29416329 0.90 MEN1 (0.66) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL29353328 0.81 MEN1 (0.56) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL2863122 0.81 MEN1 (0.56) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL14255284 0.80 MEN1 (1.00) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL31222678 0.80 MAPT (0.75) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL28737009 0.79 MAPT (0.73) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL305974 0.78 MAPT (1.00) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL305975 0.78 MAPT (1.00) MEN1KMT2AMAPTCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836568-A Method for improving dye solubility 色如丹(湖北)影像色素有限公司 2023-10-03 — — CN claimed
CN-122004563-A Article having structural color and method of making a structural colored article 耐克创新有限合伙公司 2026-05-12 — — CN disclosed
EP-3797623-B1 ARTICLES INCLUDING COATED FIBERS AND METHODS OF MAKING COATED FIBERS AND ARTICLES NIKE INNOVATE CV (US) 2025-11-26 — — EP disclosed
US-12447673-B2 Three-dimensional printing with organic dye radiation absorbers PERIDOT PRINT LLC (US) 2025-10-21 — — US disclosed
US-12442955-B2 Structurally-colored articles and methods for making and using structurally-colored articles NIKE, INC. (US) 2025-10-14 — — US disclosed
US-20250306245-A1 STRUCTURALLY-COLORED ARTICLES AND METHODS OF MAKING AND USING STRUCTURALLY-COLORED ARTICLES NIKE, INC. 2025-10-02 — — US disclosed
US-12426670-B2 Midsole structure of an article of footwear including mesh NIKE, INC. (US) 2025-09-30 — — US disclosed
US-12360288-B2 Structurally-colored articles and methods of making and using structurally-colored articles NIKE, INC. (US) 2025-07-15 — — US disclosed
US-20250204635-A1 ARTICLES INCLUDING COATED FIBERS AND METHODS OF MAKING COATED FIBERS AND ARTICLES NIKE, INC. 2025-06-26 — — US disclosed
US-20250185753-A1 ARTICLES AND METHODS OF MAKING ARTICLES INCLUDING A COATING NIKE, INC. 2025-06-12 — — US disclosed
CN-111511240-B Articles comprising coated fibers and methods of making coated fibers and articles 耐克创新有限合伙公司 2022-04-12 — — CN disclosed
US-20220107443-A1 STRUCTURALLY-COLORED ARTICLES AND METHODS FOR MAKING AND USING STRUCTURALLY-COLORED ARTICLES NIKE, INC. 2022-04-07 — — US disclosed
CN-111880256-B Structurally colored articles and methods of making and using structurally colored articles 耐克创新有限合伙公司 2022-03-08 — — CN disclosed
US-20220061464-A1 ARTICLES, BLADDERS AND METHODS OF MAKING ARTICLES AND BLADDERS NIKE, INC. 2022-03-03 — — US disclosed
CN-114073356-A Method for manufacturing articles using foam particles 耐克创新有限合伙公司 2022-02-22 — — CN disclosed
CN-114073355-A Method for manufacturing articles using foam particles 耐克创新有限合伙公司 2022-02-22 — — CN disclosed
US-20220040916-A1 METHODS OF MANUFACTURING ARTICLES UTILIZING FOAM PARTICLES NIKE, INC. 2022-02-10 — — US disclosed
EP-3946915-A1 METHODS OF MANUFACTURING ARTICLES HAVING FOAM PARTICLES Nike Innovate C.V. (US) 2022-02-09 — — EP disclosed
US-11241826-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2022-02-08 — — US disclosed
CN-108587237-A A kind of polymolecularity acid dyes and preparation method thereof 浩沙实业(福建)有限公司 2018-09-28 — — CN disclosed
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