Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783900 | 0.88 | CA1 (0.39) | CA1BLMCYP1A2L3MBTL1SLC1A3 | |
| SCHEMBL2821206 | 0.80 | CA1 (0.33) | CA1L3MBTL1 | |
| SCHEMBL27726679 | 0.78 | L3MBTL1 (0.34) | CA1ALDH1A1L3MBTL1 | |
| SCHEMBL17376827 | 0.77 | CA1 (0.34) | CA1BLMMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5052831 | 0.77 | MEN1 (0.31) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL8678816 | 0.77 | TET2 (0.31) | CA1BLML3MBTL1 | |
| SCHEMBL3896850 | 0.76 | GRM2 (0.36) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL14920098 | 0.76 | L3MBTL1 (0.42) | CA1BLMMEN1ALDH1A1CYP1A2 | |
| SCHEMBL37688 | 0.76 | TSHR (0.39) | CA1BLMMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1033008 | 0.75 | ALDH1A1 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646214-B | The preparation method of ethyl isoamyl-malonic acid diethylester | 潍坊晶润化工有限公司 | 2018-02-13 | — | — | CN | claimed |
| CN-105646214-A | Preparation method of diethyl ethylisopentylmalonate | 潍坊晶润化工有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-109666160-B | Dynamic polymer with hybrid cross-linked network | 厦门天策材料科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |
| CN-105646214-B | The preparation method of ethyl isoamyl-malonic acid diethylester | 潍坊晶润化工有限公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-105646214-B | The preparation method of ethyl isoamyl-malonic acid diethylester | 潍坊晶润化工有限公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-105646214-B | The preparation method of ethyl isoamyl-malonic acid diethylester | 潍坊晶润化工有限公司 | 2018-02-13 | — | — | CN | disclosed |
| US-RE41289-E1 | Ultrashort acting hypnotic barbiturates | ARYX THERAPEUTICS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7041673-B2 | High speed metabolism; antiepileptic agents; anesthetics; central nervous system disorders; anxiolytic agents | ARYX THERAPEUTICS, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20040167143-A1 | Ultrashort acting hypnotic barbiturates | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2004-08-26 | — | — | US | disclosed |
| US-6683086-B2 | DERIVATIVES OF BARBITURIC AND THIOBARBITURIC ACIDS; RAPIDLY METABOLIZED BY BLOOD AND TISSUE ENZYMES TO FORM POLAR METABOLITES WITH NO HYPNOTIC ACTIVITY AND WHICH ARE RAPIDLY ELIMINATED | ARYX THERAPEUTICS | 2004-01-27 | — | — | US | disclosed |
| US-20030100575-A1 | Ultrashort acting hypnotic barbiturates | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2003-05-29 | — | — | US | disclosed |
| EP-1276728-A2 | ULTRASHORT ACTING HYPNOTIC BARBITURATES | ARYx Therapeutics (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6387914-B2 | PROVIDING SEDATIVE-HYPNOTIC TREATMENT BY ADMINISTERING BARBITURATE DERIVATIVE COMPOUND | ARYX THERAPEUTICS | 2002-05-14 | — | — | US | disclosed |
| US-20020013330-A1 | Ultrashort acting hypnotic barbiturates | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2002-01-31 | — | — | US | disclosed |
| WO-2001081319-A2 | ULTRASHORT ACTING HYPNOTIC BARBITURATES | ARYX THERAPEUTICS (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167143-A1 | Ultrashort acting hypnotic barbiturates | GABRR1, GABRA1, GABRR2 | CA1 137/4885BLM 4795/4885MEN1 4212/4885 |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, MRPS18A | CA1 2605/4885BLM 3608/4885MEN1 1772/4885 |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | CA1 2620/4885BLM 3948/4885MEN1 1107/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | CA1 2687/4885BLM 2838/4885MEN1 2488/4885 |
| US-20030100575-A1 | Ultrashort acting hypnotic barbiturates | GABRR1, GABRA1, GABRR2 | CA1 137/4885BLM 4795/4885MEN1 4212/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | CA1 3481/4885BLM 2264/4885MEN1 1056/4885 |
| US-20020013330-A1 | Ultrashort acting hypnotic barbiturates | GABRR1, GABRA1, GABRR2 | CA1 137/4885BLM 4795/4885MEN1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.