Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046429 | 0.88 | DRD2 (0.42) | TSHRNPSR1DRD2DRD1DRD4 | |
| SCHEMBL28024239 | 0.83 | BRD4 (0.42) | NPSR1PDE5ASLC6A4SLC6A3LMNA | |
| SCHEMBL19385185 | 0.78 | RORC (0.49) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27979570 | 0.74 | SLC18A3 (0.33) | TSHRLMNAALDH1A1RIPK1 | |
| SCHEMBL28790708 | 0.74 | PDE5A (0.36) | TSHRNPSR1PDE5ALMNAPOLB | |
| SCHEMBL27958057 | 0.74 | HTT (0.43) | TSHRSLC6A4SLC6A3POLBKDM1A | |
| SCHEMBL27979665 | 0.74 | ACMSD (0.52) | POLBRECQLALDH1A1ALOX5 | |
| SCHEMBL28822639 | 0.73 | ALDH1A1 (0.36) | TSHRLMNAALDH1A1RIPK1 | |
| SCHEMBL28103918 | 0.73 | USP30 (0.41) | TSHRDRD2PDE5ALMNARECQL | |
| SCHEMBL21381960 | 0.73 | DRD2 (0.48) | TSHRNPSR1DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-A | 1- cyano-pyrolidin derivative as DUB inhibitor | 特殊治疗有限公司 | 2018-11-23 | — | — | CN | disclosed |