Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714906 | 0.74 | GRM4 (0.43) | EGFRFBP1TDO2GRM4AKT1 | |
| SCHEMBL1544963 | 0.74 | PTGDR2 (0.36) | EGFRFBP1ALDH1A1KMT2ATSHR | |
| SCHEMBL9844844 | 0.73 | RAPGEF4 (0.45) | MEN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL718612 | 0.72 | CA3 (0.42) | EGFRFBP1ALDH1A1 | |
| SCHEMBL17787791 | 0.68 | EGFR (0.32) | EGFRFBP1 | |
| SCHEMBL2897973 | 0.68 | NFE2L2 (0.36) | EGFRFBP1ALDH1A1 | |
| SCHEMBL2809900 | 0.68 | ESR1 (0.45) | — | |
| SCHEMBL19294196 | 0.68 | RAPGEF4 (0.42) | TDO2GRM4MEN1ALDH1A1MAPT | |
| SCHEMBL2812282 | 0.68 | TRPV4 (0.47) | EGFRFBP1 | |
| SCHEMBL5958536 | 0.68 | PYCR1 (0.39) | EGFRFBP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790122-A | Heterocyclic compound | 武田药品工业株式会社 | 2019-05-21 | — | — | CN | disclosed |